Miền đông
| # | CLB | Trận | Hiệu số | Điểm |
|---|---|---|---|---|
| 1 |  Philadelphia Union THTTB | 20 | +15 | 40 |
| 2 |  FC Cincinnati HBTTT | 20 | +5 | 39 |
| 3 |  Nashville SC HHTTT | 20 | +13 | 38 |
| 4 |  Columbus Crew HBTTT | 20 | +7 | 37 |
| 5 |  Orlando City SC BBTTB | 20 | +11 | 33 |
| 6 |  New York City FC BHTBT | 20 | +5 | 31 |
| 7 |  Inter Miami HBHTT | 16 | +9 | 29 |
| 8 |  New York Red Bulls TTBHH | 20 | +8 | 29 |
| 9 |  Chicago Fire TTBBT | 19 | +4 | 28 |
| 10 |  Charlotte BTBBB | 20 | -2 | 25 |
| 11 |  New England Revolution HTBBH | 18 | +3 | 24 |
| 12 |  DC United HTBBB | 20 | -22 | 18 |
| 13 |  Toronto FC BBHTB | 20 | -5 | 17 |
| 14 |  Atlanta United FC TTBBB | 19 | -15 | 17 |
| 15 |  CF Montreal BBTBT | 20 | -19 | 14 |
Miền tây
| # | CLB | Trận | Hiệu số | Điểm |
|---|---|---|---|---|
| 1 |  San Diego FC BTTTT | 20 | +16 | 39 |
| 2 |  Vancouver Whitecaps HTBBT | 19 | +16 | 38 |
| 3 |  Minnesota United FC HTBTH | 20 | +10 | 34 |
| 4 |  Portland Timbers BTTHB | 19 | +1 | 30 |
| 5 |  Seattle Sounders TTBBT | 19 | +2 | 29 |
| 6 |  San Jose Earthquakes TBHTH | 20 | +8 | 27 |
| 7 |  Los Angeles FC THHTB | 17 | +6 | 26 |
| 8 |  Colorado Rapids BBBTH | 20 | -5 | 26 |
| 9 |  Austin HBTTB | 20 | -8 | 26 |
| 10 |  Houston Dynamo TBBBT | 20 | -6 | 23 |
| 11 |  FC Dallas HHTBB | 19 | -9 | 21 |
| 12 |  Sporting Kansas City TBBTH | 20 | -6 | 20 |
| 13 |  Real Salt Lake BHBTH | 19 | -7 | 19 |
| 14 |  St. Louis City TBHBB | 20 | -12 | 15 |
| 15 |  Los Angeles Galaxy BTHBH | 20 | -23 | 9 |
Supporters Shield
| # | CLB | Trận | Hiệu số | Điểm |
|---|---|---|---|---|
| 1 | Philadelphia Union THTTB | 20 | +15 | 40 |
| 2 | San Diego FC BTTTT | 20 | +16 | 39 |
| 3 | FC Cincinnati HBTTT | 20 | +5 | 39 |
| 4 | Vancouver Whitecaps HTBBT | 19 | +16 | 38 |
| 5 | Nashville SC HHTTT | 20 | +13 | 38 |
| 6 | Columbus Crew HBTTT | 20 | +7 | 37 |
| 7 | Minnesota United FC HTBTH | 20 | +10 | 34 |
| 8 | Orlando City SC BBTTB | 20 | +11 | 33 |
| 9 | New York City FC BHTBT | 20 | +5 | 31 |
| 10 | Portland Timbers BTTHB | 19 | +1 | 30 |
| 11 | Inter Miami HBHTT | 16 | +9 | 29 |
| 12 | New York Red Bulls TTBHH | 20 | +8 | 29 |
| 13 | Seattle Sounders TTBBT | 19 | +2 | 29 |
| 14 | Chicago Fire TTBBT | 19 | +4 | 28 |
| 15 | San Jose Earthquakes TBHTH | 20 | +8 | 27 |
| 16 | Los Angeles FC THHTB | 17 | +6 | 26 |
| 17 | Colorado Rapids BBBTH | 20 | -5 | 26 |
| 18 | Austin HBTTB | 20 | -8 | 26 |
| 19 | Charlotte BTBBB | 20 | -2 | 25 |
| 20 | New England Revolution HTBBH | 18 | +3 | 24 |
| 21 | Houston Dynamo TBBBT | 20 | -6 | 23 |
| 22 | FC Dallas HHTBB | 19 | -9 | 21 |
| 23 | Sporting Kansas City TBBTH | 20 | -6 | 20 |
| 24 | Real Salt Lake BHBTH | 19 | -7 | 19 |
| 25 | DC United HTBBB | 20 | -22 | 18 |
| 26 | Toronto FC BBHTB | 20 | -5 | 17 |
| 27 | Atlanta United FC TTBBB | 19 | -15 | 17 |
| 28 | St. Louis City TBHBB | 20 | -12 | 15 |
| 29 | CF Montreal BBTBT | 20 | -19 | 14 |
| 30 | Los Angeles Galaxy BTHBH | 20 | -23 | 9 |
Vòng tranh chức vô địch
TThắng
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