| # | Cầu thủ | CLB | Số bàn |
|---|---|---|---|
| 1 |  Lionel Messi | Inter Miami CF | 18 |
| 2 |  Sam Surridge | Nashville SC | 18 |
| 3 |  Evander Ferreira | FC Cincinnati | 15 |
| 4 |  Tai Baribo | Philadelphia Union | 14 |
| 5 |  Hugo Cuypers | Chicago Fire FC | 13 |
| 6 |  Martin Ojeda | Orlando City | 13 |
| 7 |  Dejan Joveljic | Sporting Kansas City | 13 |
| 8 |  Eric Maxim Choupo-Moting | New York Red Bulls | 13 |
| 9 |  Denis Bouanga | Los Angeles FC | 13 |
| 10 |  Petar Musa | FC Dallas | 12 |
| 11 |  Alonso Martinez | New York City FC | 12 |
| 12 |  Diego Rossi | Columbus Crew | 12 |
| 13 |  Kevin Denkey | FC Cincinnati | 12 |
| 14 |  Brian White | Vancouver Whitecaps | 11 |
| 15 |  Anders Dreyer | 11 | |
| 16 |  Cristian Arango | San Jose Earthquakes | 11 |
| 17 |  Hany Mukhtar | Nashville SC | 11 |
| 18 |  Prince Osei Owusu | CF Montreal | 11 |
| 19 |  Marco Pasalic | Orlando City | 10 |
| 20 |  Milan Iloski | 10 |
Major League Soccer
MỹMessi - Inter Miami